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This article was considered for deletion at Wikipedia on February 20 2015. This is a backup of Wikipedia:EPLAR. All of its AfDs can be found at Wikipedia:Special:PrefixIndex/Wikipedia:Articles_for_deletion/EPLAR, the first at Wikipedia:Wikipedia:Articles_for_deletion/EPLAR. Purge

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Template:Self-published Template:COI ePLAR – the echocardiographic Pulmonary to Left Atrial Ratio, is a proposed numeric parameter used to assess the pulmonary circulation and its relationship with left atrial pressure. It is calculated from the standard transthoracic Doppler echocardiogram parameter tricuspid regurgitation peak continuous wave Doppler velocity (TRVmax) measure in meters/second divided by the ratio of transmitral peak pulse-wave Doppler E-wave velocity : Doppler Tissue Velocity peak E wave of the medial mitral annulus (E/e’). ePLAR (m/s) = TRVmax / mitral E/e’. [no citations needed here]

Initial validation studies comparing ePLAR to cardiac catheterization of the right heart are underway, testing predictive values. Specifically, ePLAR sensitivity and specificity for differentiation pre-capillary pulmonary hypertension (which may respond to modern specific pulmonary vasodilator drugs) from post-capillary physiology pulmonary hypertension secondary to left heart disease will be tested.[no citations needed here]

The ePLAR was conceptualized on 21.9.2014 by Dr Gregory M Scalia (Cardiologist, the University of Queensland, The Prince Charles Hospital) during a lecture regarding the invasive assessment of pulmonary hypertension patients.[no citations needed here] This author had developed several Doppler echocardiography numeric parameters over the last two decades to assess cardiac diastolic function [1][2] and Cardiac shunt defects with the The Relative Atrial Index (RAI).[3]

See also


  1. Non-Invasive Assessment of the Ventricular Relaxation Time Constant (τ) in Humans by Doppler Echocardiography.Gregory M. Scalia, Neil L. Greenberg, Patrick M. McCarthy, James D. Thomas, Pieter M. Vandervoort. Circulation 1997;95:151-5
  2. Color M-mode and Doppler-derived tau (τ) as practical advances in clinical diastology - the TauCoMM project. G.M. Scalia and D.J. Burstow. Heart, Lung and Circulation 1999 Vol. 9, Issue 3, Page A13.
  3. “The Relative Atrial Index (RAI) – A Novel, Simple, Reliable and Robust Transthoracic Echocardiographic Indicatory of Atrial Defects”. Natalie F Kelly, Darren Walters, Lisa Hourigan, Darryl J Burstow, Gregory M Scalia. J Am Soc Echocardiogr 2010;23:275-81.

External links